UCLA vs Oregon Prediction and Odds: Ducks -11.5 With Dante Moore in Question

No. 13 Oregon is an 11.5-point favorite over No. 21 UCLA at Autzen Stadium, with a total of 59.5, as of Tuesday morning, October 6, 2026. That turns into a market prediction of Oregon 35.5, UCLA 24. The catch: Oregon quarterback Dante Moore is working back from a concussion, and his status for Saturday has not been announced.
UCLA vs Oregon odds at every book
UCLA at Oregon kicks off Saturday, October 10, 2026, at 3:30 PM ET on CBS. These are the lines on SportsbookReview's board as of Tuesday, October 6, about 9 AM ET, cross-checked against FOX Sports and CBS Sports (both Oregon -11.5, total 59.5). Compare prices on our sportsbooks page.
| Book | Spread | Moneyline (UCLA / ORE) | Total |
|---|---|---|---|
| BetMGM | ORE -11.5 | +360 / -450 | 59.5 |
| bet365 | ORE -11.5 | +350 / -450 | 59.5 |
| DraftKings | ORE -11.5 | +360 / -470 | 59.5 |
| FanDuel | ORE -11.5 | +340 / -465 | 59.5 |
| Fanatics | ORE -12.5 | +360 / -475 | 59.5 |
| BetRivers | ORE -12.5 | +370 / -529 | 59.5 |
| Caesars | ORE -11.5 | +340 / -441 | 59.5 |
UCLA vs Oregon prediction from the odds
With Oregon -11.5 and a 59.5 total, the implied final is Oregon (59.5 + 11.5) / 2 = 35.5 and UCLA 24. The line has come down a point and a half since it opened at Oregon -13, and our Sunday preview had it at -12.5 to -13.5. The most likely reason is the uncertainty at quarterback for Oregon, but no book or outlet has said so directly, so treat that as our read of the timing, not a fact. If Oregon rules Moore out, expect the spread to drop further.
Is Dante Moore playing against UCLA?
Not confirmed yet. Dante Moore was hit late on a slide in the second quarter at USC on September 26 and was diagnosed with a concussion, per Field Level Media, theScore and CBS Sports. On Monday, October 5, he returned to practice in a helmet and shoulder pads and did "a little work," according to coach Dan Lanning, as reported by Yahoo Sports and Autzen Zoo. Oregon's first official availability report for the UCLA game is due Wednesday, October 7, at 5 PM Pacific. If Moore cannot go, Dylan Raiola, the Nebraska transfer who finished Oregon's 41-27 win at USC, is the expected starter. As of October 6, Moore's status for Saturday is unresolved.
How UCLA and Oregon got here
| Date | UCLA (4-0) | Oregon (3-1) |
|---|---|---|
| Sept 5 | W 45-24 at California | W 34-27 vs Boise State |
| Sept 12 | W 28-10 vs San Diego State | L 39-31 at Oklahoma State |
| Sept 18-19 | W 52-38 vs Purdue | W 84-0 vs Portland State (Fri) |
| Sept 26 | W 54-3 at Maryland | W 41-27 at USC |
| Oct 3 | Bye | Bye |
UCLA: a 4-0 start in Bob Chesney's first season
UCLA went 3-9 in 2025. Under first-year coach Bob Chesney, hired from James Madison, the Bruins are 4-0, ranked for the first time since 2023, and scoring 44.8 points per game while allowing 18.75. Running back Wayne Knight, who followed Chesney from James Madison, has 445 rushing yards and a nation-leading 9 rushing touchdowns, per SI and Yahoo Sports. Quarterback Nico Iamaleava, the Tennessee transfer, has 4 touchdown passes. Chesney has seen Autzen before: his James Madison team lost 51-34 there in the College Football Playoff first round in December 2025.
Oregon: one loss and a quarterback question
Oregon lost 39-31 at Oklahoma State on September 12 as the No. 6 team in the country, then beat Portland State 84-0 and won 41-27 at USC, its fifth straight win over the Trojans. The Ducks are scoring 47.5 points per game and allowing 23.25, based on their four results. Before the injury, Moore threw for 378 yards and 3 touchdowns against Boise State. Dan Lanning is in his fifth season.
UCLA vs Oregon series history
Oregon has won five straight meetings with UCLA, and UCLA has not won at Autzen Stadium since 2004, per Yahoo Sports and Winsipedia's series data. The last three games:
| Date | Result | Site |
|---|---|---|
| Sept 28, 2024 | Oregon 34, UCLA 13 | Rose Bowl |
| Oct 22, 2022 | Oregon 45, UCLA 30 | Autzen Stadium |
| Oct 23, 2021 | Oregon 34, UCLA 31 | Rose Bowl |
Other UCLA and Oregon injuries
Beyond Moore, the injury picture is thin before the first official reports. UCLA quarterback Nico Iamaleava has taken several hits this season but has not been listed as doubtful anywhere. Both teams were idle on October 3, so neither has a rest edge. We will update this section after Oregon's Wednesday availability report.
No pick on this page. Our handicapped side for UCLA at Oregon is available through premium picks (Pay After You Win: charged only on a win), and free plays go up on free picks.
UCLA vs Oregon questions
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