Missouri vs Ole Miss Prediction and Odds: Week 7 2026
No. 13 Missouri goes to No. 9 Ole Miss off a 27-6 win over Texas A&M, and the books make Ole Miss a 6-point favorite at most major books (as of Sunday night, October 11, 2026; DraftKings has -5.5), with a total of 59.5. Missouri has beaten Ole Miss six straight times, and both teams have a shared reference point: Florida, which beat Ole Miss 52-28 and then lost 45-17 at Missouri. The betting market's Missouri vs Ole Miss prediction is Ole Miss 32.5, Missouri 27.
Missouri vs Ole Miss odds at every book
Here is the board for Missouri at Ole Miss on Saturday, October 17, 2026, at 3:30 PM ET at Vaught-Hemingway Stadium in Oxford, as of Sunday night, October 11, 2026. The TV network had not been finalized. Books split from Ole Miss -5.5 at DraftKings to -6.5 at FanDuel and BetRivers, and the Las Vegas books on VegasInsider show -6 to -6.5. If you like Missouri, +6.5 is the number to look for; if you like Ole Miss, DraftKings' -5.5 is the best price. Compare where you have accounts on our sportsbooks page.
| Book | Spread | Moneyline (MIZ / MISS) | Total |
|---|---|---|---|
| BetMGM | Ole Miss -6 | +180 / -220 | 59.5 |
| bet365 | Ole Miss -6 | +180 / -220 | 59.5 |
| DraftKings | Ole Miss -5.5 | +185 / -225 | 59.5 |
| FanDuel | Ole Miss -6.5 | +164 / -200 | 59.5 |
| Fanatics | Ole Miss -6 | +185 / -225 | 59.5 |
| BetRivers | Ole Miss -6.5 | +180 / -230 | 60.5 |
| Caesars | Ole Miss -6 | +186 / -235 | not posted |
Missouri vs Ole Miss prediction from the betting odds
The spread has barely moved from the Ole Miss -6 opener, and the total has held at 59.5, so this is a market that has made up its mind early. If you like either side, shopping for the best number across books is worth the effort.
How Missouri and Ole Miss got here
Missouri's only loss is 31-24 at Mississippi State on September 26, and it has won its last two by a combined 72-23. Ole Miss's only loss is 52-28 at Florida on September 26, and it came out of its bye with a 52-17 win at Vanderbilt.
| Date | Missouri | Ole Miss |
|---|---|---|
| Week 1 | W 54-14 vs Arkansas-Pine Bluff | W 41-38 vs Louisville (Nashville) |
| Week 2 | W 38-21 at Kansas | W 41-9 vs Charlotte |
| Week 3 | W 27-17 vs Troy | W 32-24 vs LSU |
| Week 4 | L 24-31 at Mississippi State | L 28-52 at Florida |
| Week 5 | W 45-17 vs Florida | Bye |
| Week 6 | W 27-6 vs Texas A&M | W 52-17 at Vanderbilt |
Missouri: Jamal Roberts and back-to-back 200-yard games
Missouri running back Jamal Roberts carried 34 times for 222 yards and two touchdowns against Texas A&M, his second straight 200-yard game after 211 yards and three touchdowns against Florida.
Ole Miss: Trinidad Chambliss and a healthy Kewan Lacy
Ole Miss quarterback Trinidad Chambliss threw for 213 yards and three touchdowns and ran for another in the 52-17 win at Vanderbilt, where Ole Miss led 42-3 at halftime and scored 24 points off four turnovers. Running back Kewan Lacy returned in that game after missing the Florida loss, with seven carries for 39 yards and a touchdown.
Missouri and Ole Miss injury report
No Week 7 SEC availability report is out yet; the first one comes Wednesday night. These are the statuses confirmed by at least two outlets as of October 11.
| Player | Team | Pos | Status |
|---|---|---|---|
| Kewan Lacy | Ole Miss | RB | Returned Oct 10 after missing the Florida game |
| Ahmad Hardy | Missouri | RB | Out; no return timeline |
Missouri vs Ole Miss series history
Missouri leads the all-time series 7-1 and has won six straight meetings; Ole Miss's only win came in 1974. This is Missouri's first trip to Oxford since 2013.
| Date | Site | Result |
|---|---|---|
| Oct 12, 2019 | Columbia | Missouri 38, Ole Miss 27 |
| Nov 23, 2013 | Oxford | Missouri 24, Ole Miss 10 |
| Sept 8, 2007 | Oxford | Missouri 38, Ole Miss 25 |
Missouri vs Ole Miss questions
Who is favored in Missouri vs Ole Miss?+
What is the Missouri vs Ole Miss prediction from the odds?+
What is the all-time record between Missouri and Ole Miss?+
What time is Missouri vs Ole Miss?+
How did Missouri do against Texas A&M?+
Sports betting involves risk and is intended for entertainment purposes for adults 21 and older. Please bet responsibly. If you or someone you know has a gambling problem, call 1-800-GAMBLER.