College Football Week 7 Odds and Preview: Ohio State at Indiana Leads the Slate
Texas lost its unbeaten record to Oklahoma, Oregon lost at home to UCLA, and Kentucky beat LSU in overtime, and the books have already posted the next round. The college football Week 7 odds for Saturday, October 17, 2026, are headlined by Ohio State at Indiana, with Ohio State a 3.5 to 4.5 point favorite as of Sunday morning, October 11. That line opened at Ohio State -2.5. Alabama is -6.5 at Tennessee, Ole Miss is -6 to -6.5 against Missouri, and Notre Dame is -11.5 to -13.5 at BYU.
Week 6 in one paragraph
Saturday, October 10 reshaped the top of the sport. Oklahoma beat No. 1 Texas 27-24 with a late field goal, Georgia beat Alabama 20-17, UCLA won 17-15 at Oregon by stopping a late two-point try, and Kentucky beat LSU 35-34 in overtime. Indiana rallied to win 20-17 at Nebraska, Ohio State beat Maryland 45-16, Notre Dame beat Stanford 58-7, and South Carolina won 38-19 at Florida. Scores verified on CBS Sports and Yahoo Sports.
College football Week 7 odds for every big game
| Kickoff | Game | Spread | Total | Moneyline (FanDuel) |
|---|---|---|---|---|
| 12:00 PM | Ohio State at Indiana | Ohio State -3.5 to -4.5 | 48.5 to 50 | -178 / +146 |
| 12:00 PM | Florida at Texas | Texas -10 to -10.5 | 53.5 to 54.5 | +270 / -345 |
| 12:00 PM | Mississippi State at LSU | LSU -11.5 to -12 | 59.5 | +315 / -410 |
| 3:30 PM | Alabama at Tennessee | Alabama -6.5 | 55.5 to 56.5 | -235 / +190 |
| 3:30 PM | Missouri at Ole Miss | Ole Miss -6 to -6.5 | 58.5 | +188 / -230 |
| 3:30 PM | Auburn at Georgia | Georgia -18.5 to -19.5 | 49.5 to 50.5 | +810 / -1450 |
| 3:30 PM | Arizona State at Texas Tech | Texas Tech -12.5 | 49.5 to 50.5 | +385 / -520 |
| 7:00 PM | Florida State at Miami (FL) | Miami -20.5 to -21.5 | 55.5 | +980 / -2000 |
| 7:30 PM | Notre Dame at BYU | Notre Dame -11.5 to -13.5 | 46.5 to 48.5 | -450 / +340 |
| 7:30 PM | Oklahoma State at Houston | Houston -3.5 | 58.5 to 59.5 | +136 / -164 |
| 7:30 PM | Wisconsin at UCLA | UCLA -4.5 | 45.5 | +162 / -196 |
| 10:15 PM | Utah at Colorado | Utah -14.5 | 49.5 to 50.5 | -720 / +500 |
| TBA | Nebraska at Oregon | Off the board | Off the board | n/a |
Spreads and totals are the range across BetMGM, bet365, DraftKings, FanDuel, Fanatics, BetRivers and Caesars on SportsbookReview's odds board, cross-checked against the Covers odds board. Moneylines are away / home at FanDuel. Not every book had posted every game on Sunday morning.
Biggest college football line moves for Week 7
| Game | Opened | Now | Direction |
|---|---|---|---|
| Ohio State at Indiana | Ohio State -2.5 | Ohio State -3.5 to -4.5 | Toward Ohio State |
| Alabama at Tennessee | Alabama -4.5 | Alabama -6.5 | Toward Alabama |
| Notre Dame at BYU | Notre Dame -10.5 | Notre Dame -11.5 to -13.5 | Toward Notre Dame |
| Florida State at Miami | Miami -19.5 | Miami -20.5 to -21.5 | Toward Miami |
| Mississippi State at LSU | LSU -12.5 | LSU -11.5 to -12 | Toward Mississippi State |
| Wisconsin at UCLA | UCLA -5.5 | UCLA -4.5 | Toward Wisconsin |
| Utah at Colorado (total) | 52.5 | 49.5 to 50.5 | Down 2 to 3 points |
"Opened" is the opening number on SportsbookReview's board for the game. Early-week college lines are thin and can move a lot by Saturday.
The early money went one way: favorites. Ohio State moved from -2.5 to as high as -4.5 at Fanatics and BetRivers, Alabama from -4.5 to -6.5 at every book, and Notre Dame from -10.5 to as high as -13.5. The two moves the other way were small ones toward Mississippi State and Wisconsin. Our guide to line movement explains how news and money move numbers, which matters this week for Oregon, Mississippi State and Tennessee.
Ohio State vs Indiana odds
Both teams won close on Saturday in different ways: Ohio State pulled away from Maryland 45-16, while Indiana needed two fourth-quarter touchdowns to win 20-17 at Nebraska after trailing by 11. The market has moved 1.5 to 2 points toward Ohio State since the open, past the field goal, which is the number that matters most in a game this tight. Ohio State played without several regulars against Maryland, and their status for Indiana had not been announced as of Sunday; watch the Big Ten availability report midweek.
Alabama vs Tennessee odds
Alabama lost 20-17 at Georgia and still took the early money: every book moved from 4.5 to 6.5. Tennessee beat Arkansas 24-17, but Faizon Brandon was limited to emergency duty with a shoulder injury and George MacIntyre started at quarterback. Tennessee's starter is the biggest unknown in this game. Alabama also has injury questions after Georgia: receiver Ryan Coleman-Williams (head) and center Racin Delgatty (lower leg) did not finish the game.
Missouri vs Ole Miss odds
Ole Miss beat Vanderbilt 52-17 behind Trinidad Chambliss (213 passing yards, three touchdown passes and a rushing score), and Missouri beat Texas A&M 27-6 with Austin Simmons at quarterback. The spread has barely moved, but the total is up a point to 58.5 at every book. Missouri running back Ahmad Hardy was reported as expected to miss this game in an October 6 report; we have only one source on it, so treat his status as unconfirmed until the SEC availability report.
Notre Dame vs BYU odds
BYU beat Iowa State 24-10, yet the line has moved toward Notre Dame by one to three points since the open. The spread range is unusually wide: DraftKings has Notre Dame -12.5, FanDuel -11.5, Fanatics -13 and BetRivers -13.5, a two-point gap worth shopping. BYU running back LJ Martin is expected to miss at least a month, and Notre Dame cornerback Leonard Moore (concussion) missed Stanford, with his status for BYU unresolved.
Key college football injuries for Week 7
Statuses as of October 11, 2026, each confirmed by at least two reputable sources (team statements, On3, Yahoo Sports, Bleacher Report and others). Statuses can change before kickoff; the SEC and Big Ten availability reports start Wednesday, October 14.
| Player | Team | Pos | Status | Reported |
|---|---|---|---|---|
| Dante Moore | Oregon | QB | Concussion (Sept. 26); missed the UCLA game. Coach Dan Lanning would not commit to a return date. Unresolved for Nebraska. | Oct. 10 to 11 |
| Dylan Raiola | Oregon | QB | Not injured. Started vs. UCLA and was benched late for Brock Thomas. Oregon has not named a starter. | Oct. 10 to 11 |
| Kamario Taylor | Mississippi State | QB | Lower leg/ankle; day-to-day. Coach Jeff Lebby said the Wednesday injury report will settle it. Unresolved. | Oct. 3 to 4 |
| Faizon Brandon | Tennessee | QB | Shoulder; emergency use only vs. Arkansas while George MacIntyre started. Unresolved. | Oct. 10 |
| Ryan Coleman-Williams | Alabama | WR | Head injury vs. Georgia; did not return. Unresolved. | Oct. 10 to 11 |
| Racin Delgatty | Alabama | C | Lower leg vs. Georgia; "will be evaluated." Unresolved. | Oct. 10 to 11 |
| Leonard Moore | Notre Dame | CB | Concussion; missed Stanford. Notre Dame hopes to have him for BYU. Unresolved. | Oct. 10 |
| LJ Martin | BYU | RB | Lower body; expected to miss at least a month. | Oct. 7 to 8 |
| Vernell Brown III | Florida | WR | Knee strain; missed South Carolina. Unresolved. | Oct. 10 |
| Whit Weeks | LSU | LB | Fractured fibula; out, with a possible November return. | Sept. 29 to Oct. 10 |
The game most exposed to quarterback news is Nebraska at Oregon, which is off the board at every book we checked. Dante Moore missed the UCLA loss with a concussion, Dylan Raiola was benched late in that game, and Oregon has not said who starts. Mississippi State at LSU carries the same question: Kamario Taylor's status will not be clear until Mississippi State's Wednesday report.
Other Week 7 games
Texas hosts Florida as a 10 to 10.5 point favorite after both lost on Saturday. Georgia is an 18.5 to 19.5 point favorite over Auburn, and Miami is a 20.5 to 21.5 point favorite over Florida State, which lost 44-20 to Louisville. Texas Tech is -12.5 against Arizona State, Houston is -3.5 against Oklahoma State, UCLA is -4.5 against Wisconsin, and Utah is -14.5 at Colorado in the late window.
College football Week 7 betting questions
What is the spread for Ohio State vs Indiana?+
Who is favored in Alabama vs Tennessee?+
Why is Nebraska vs Oregon off the board?+
What is the biggest spread in college football Week 7?+
When do college football injury reports come out?+
Last week's preview: college football Week 6 preview. New to spreads? Read what a point spread is or start at the betting basics hub.
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