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Major NFL Injuries 2026: Season-Enders, QBs and the IR List

Major NFL Injuries 2026: Season-Enders, QBs and the IR List

The 2026 NFL season is six weeks old and the injury list already reads like a playoff bracket of what-ifs. Jalen Hurts is expected to miss the rest of the season with blood clots, Jaxson Dart and De'Von Achane are done, Terry McLaurin tore a patellar tendon on Monday night, and four starting quarterbacks have already missed games. Here are the major NFL injuries of 2026 so far, with every status checked as of October 20, 2026.

Where it stands
Through Week 6, the biggest losses are Jalen Hurts (Eagles QB, blood clots, expected out for the season), Jaxson Dart (Giants QB, season-ending knee surgery), De'Von Achane (Dolphins RB, torn ACL), Terry McLaurin (Commanders WR, torn patellar tendon) and Brian Burns (Giants edge, torn ACL). Lamar Jackson and Baker Mayfield have each missed multiple starts, and Davante Adams is out 6 to 10 weeks.
4
Starting QBs who have missed games
Hurts, Dart, Jackson, Mayfield
9
In-season injuries in our table that ended a season
Weeks 1 to 6
+20,000
Eagles Super Bowl odds, best price
From +2,500 to +4,000 on Oct 12
6 to 10
Weeks Davante Adams is expected to miss
Ruptured hamstring, Oct 18

The biggest NFL injuries of 2026 so far

Every player below suffered a season-ending injury, or is expected to miss the season, during the 2026 regular season. Statuses come from team announcements and at least two major outlets, and the week numbers follow the official schedule (Week 1 opened September 9 and Week 6 closed with Monday night's 49ers win over Washington).

Season-ending injuries, 2026 regular season (as of October 20, 2026)
PlayerTeamPosInjuryWhenStatus
Jalen HurtsEaglesQBBlood clots (DVT, clots in both lungs)Disclosed Oct 19Expected out for season, on IR
Jaxson DartGiantsQBLeft knee: MCL, PCL, meniscusWeek 2 at Rams, Sep 21Season-ending surgery
De'Von AchaneDolphinsRBTorn left ACLWeek 3 vs Chiefs, Sep 27Out for season
Terry McLaurinCommandersWRTorn left patellar tendonWeek 6 at 49ers, Oct 19Out for season
Brian BurnsGiantsEdgeTorn ACLWeek 3 vs Titans, Sep 27Out for season
Edgerrin CooperPackersLBTorn AchillesWeek 4 vs Buccaneers, Oct 4Out for season
Javon HargravePackersDTTorn AchillesWeek 5 vs BearsOut for season
Durham SmytheRavensTETorn AchillesWeek 4 vs Titans, Oct 4Out for season
Arian SmithJetsWRTorn ACLWeek 2 vs Packers, Sep 20Out for season, on IR
Compiled by Guaranteed Sport Picks from team releases, NFL.com, ESPN, AP and local reporting. Preseason losses are listed in their own section below.
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Quarterback injuries in 2026: four starters have missed games

No position moves a point spread like quarterback, and 2026 has already cost four teams their starter for at least one game.

Jalen Hurts, Philadelphia Eagles: blood clots

Jalen Hurts first dealt with a blood clot in his calf around October 8 and still played the Eagles' Week 5 game against Jacksonville in London after an ultrasound cleared him. He was ruled out for Week 6, placed on injured reserve on October 17, and on October 19 the Eagles and his agent disclosed deep vein thrombosis and clots in both lungs. He is on blood thinners and multiple outlets report he is expected to miss the rest of the season, while the team says it expects a full recovery. Tanner McKee started the 25-14 home loss to Carolina, and Philadelphia is 2-4.

Jaxson Dart, New York Giants: season-ending knee surgery

Jaxson Dart was hurt on the first drive of the Giants' Week 2 Monday night loss to the Rams on September 21. The damage was to his left MCL, PCL and meniscus (the ACL was intact), and he had surgery that ends his regular season; meniscus repair usually takes four to six months. Jameis Winston has started since, and the Giants are 3-2-1.

Lamar Jackson, Baltimore Ravens: sprained left ankle

Lamar Jackson sprained his left ankle when he was sacked on the final play of the first half against Tennessee on October 4. He missed Week 5 at Atlanta and Week 6 at Cleveland, with Tyler Huntley starting both, and as of October 20 the Ravens called him day-to-day ahead of Week 7 against Cincinnati. The Ravens opened -3 for that game and sit at -2.5.

Baker Mayfield, Tampa Bay Buccaneers: dislocated throwing thumb

Baker Mayfield dislocated his right thumb late in the Week 3 loss to Minnesota on September 27. X-rays showed no fracture, but he has missed Weeks 4 through 6 and Todd Bowles has not set a return date. Rookie Jalon Daniels has started in his place, and Tampa Bay is 1-5.

Season-ending injuries beyond the quarterbacks

De'Von Achane, Miami Dolphins

De'Von Achane tore the ACL in his left knee on a non-contact play in the first quarter of Miami's 24-10 loss to Kansas City on September 27. The Dolphins lost their most explosive skill player three games into the season and are 0-5.

Terry McLaurin, Washington Commanders

Terry McLaurin went down in the first quarter of Monday's 23-17 loss in San Francisco, and Dan Quinn confirmed on October 20 that he tore the patellar tendon in his left knee. Washington is 1-4-1 and loses its top receiver for the rest of the year.

Brian Burns, New York Giants

Brian Burns tore his ACL in the fourth quarter of the Giants' 12-7 win over Tennessee on September 27, the same weekend New York was already without Dart. John Harbaugh confirmed the tear the next day.

Green Bay Packers: two Achilles tears in two weeks

Linebacker Edgerrin Cooper tore his Achilles against Tampa Bay on October 4, and defensive tackle Javon Hargrave tore his in the Week 5 win over Chicago. Micah Parsons is also still on the PUP list recovering from the torn ACL he suffered in Week 15 of 2025, with Week 9 reported as his earliest return. Green Bay is 4-2 anyway.

Baltimore tight end Durham Smythe (torn Achilles, October 4) and Jets receiver Arian Smith (torn ACL, September 20) round out the in-season list.

NFL players on injured reserve with a return in view

These players are out for weeks, not the season. Return windows are the team or reported estimates as of October 20, 2026, and they slip often (Myles Garrett was first expected back after four games).

Multi-week injuries (as of October 20, 2026)
PlayerTeamInjuryExpected return
Davante AdamsRams WRRuptured hamstring, Oct 186 to 10 weeks
Myles GarrettRams edgeKnee surgery after Week 1IR since Sep 17; not practicing this week
Tyquan ThorntonChiefs WRDislocated ankle, torn ligaments, Oct 412 to 16 weeks
Jaycee HornPanthers CBTorn quad, Sep 27About 8 weeks (estimates vary)
Michael Pittman Jr.Steelers WRFoot (plantar fascia)November 15 at the earliest
Rashawn SlaterChargers LTHigh ankle sprain, surgeryAt least 4 games from Oct 9
Anton HarrisonJaguars LTKnee, arthroscopic surgeryWeeks, possibly months
Mike OnwenuPatriots GAnkle, Sep 20At least 4 weeks from Sep 22
Mike Evans49ers WRAchilles, left MNF Oct 19Unresolved for Week 7

Two receivers are on the way back. A.J. Brown missed four games with a high ankle sprain from the opener and was activated by New England on October 17, and Kansas City's Rashee Rice missed Weeks 5 and 6 with a hamstring injury.

Preseason injuries that changed 2026 before it started

  • Jayden Higgins, Texans WR: torn ACL in an August practice, out for the season.
  • Jalon Walker, Falcons LB: torn ACL in training camp, out for the season.
  • Bryan Bresee, Saints DT: torn ACL on the first day of camp, season-ending surgery.
  • Danny Pinter, Ravens C: torn patellar tendon in a joint practice with Minnesota, on IR.
  • Alex Wright, Browns DE: torn Achilles in a joint practice with Buffalo, on IR.

Which NFL teams have been hit hardest by injuries in 2026?

Los Angeles Rams (2-4)
โœ•Davante Adams out 6 to 10 weeks
โœ•Myles Garrett on IR since Week 2
โ€ขSuper Bowl odds from +650 on Oct 12 to +1,100 to +1,200
New York Giants (3-2-1)
โœ•Starting QB Jaxson Dart lost in Week 2
โœ•Top pass rusher Brian Burns lost in Week 3
โ€ขJameis Winston at quarterback
Philadelphia Eagles (2-4)
โœ•Jalen Hurts expected out for the season
โ€ขTanner McKee starting
โ€ขSuper Bowl odds +15,000 to +20,000
Baltimore Ravens (4-2)
โœ•Lamar Jackson has missed two starts
โœ•Lost TE Durham Smythe and C Danny Pinter
โ€ขTyler Huntley started Weeks 5 and 6

How the 2026 injuries moved the betting market

The cleanest way to measure an injury is the price before and after it. These moves come from the Super Bowl board and Week 7 lines we track, using SportsbookReview and VegasInsider snapshots (lines move, so check before you bet). For more on why prices react this way, see how line movement works.

Opener vs now, compiled by Guaranteed Sport Picks
MarketBeforeNow (Oct 20)Injury news
Eagles to win Super Bowl+2,500 to +4,000 (Oct 12)+15,000 to +20,000Hurts out for season
Rams to win Super Bowl+650 (Oct 12)+1,100 to +1,200Adams 6 to 10 weeks
Cowboys at Eagles, Week 7Eagles -3 (lookahead)Cowboys -4.5 to -5.5Hurts out
Rams at Raiders, Week 7Rams -6Rams -4.5Adams out
49ers at Falcons, Week 749ers -4.549ers -3.5 to -4.5Evans unresolved
Bengals at Ravens, Week 7Ravens -3Ravens -2.5Jackson day-to-day

The Philadelphia number is the biggest swing on the board: the Eagles were a home favorite on the lookahead line and are now a 4.5 to 5.5-point home underdog to Dallas. When a status is still open, as with Jackson and Evans, books tend to hold a smaller adjustment and finish the move once the inactive list comes out about 90 minutes before kickoff. That is why shopping the number at more than one book matters most in injury weeks; our sportsbook comparison lists where to look, and live betting odds show where each line sits now.

Prediction markets react to the same news, often within minutes. Kalshi's NFL game and Super Bowl contracts trade like a price you can buy or sell, so you can get out of a position before the game ends if an injury report changes your view, and Polymarket lists its own NFL futures and game markets. If you are new to those prices, our guide on how to read Kalshi and Polymarket odds converts them to sportsbook odds.

NFL injury questions bettors ask

Is Jalen Hurts out for the 2026 season?+
Jalen Hurts is on injured reserve with deep vein thrombosis and blood clots in both lungs, disclosed on October 19, 2026, and multiple outlets report he is expected to miss the rest of the season. The Eagles say they expect a full recovery. Tanner McKee has started in his place.
Which NFL quarterbacks are injured in 2026?+
As of October 20, 2026, Jalen Hurts (Eagles, blood clots) and Jaxson Dart (Giants, knee surgery) are out for the regular season, while Lamar Jackson (Ravens, left ankle) and Baker Mayfield (Buccaneers, right thumb) have missed multiple starts with no confirmed return date.
Who has torn an ACL in the NFL in 2026?+
In-season ACL tears in 2026 include Dolphins running back De'Von Achane, Giants edge rusher Brian Burns and Jets receiver Arian Smith. Jayden Higgins (Texans), Jalon Walker (Falcons) and Bryan Bresee (Saints) tore ACLs in the preseason.
How long is Davante Adams out?+
Sean McVay said Davante Adams is expected to miss 6 to 10 weeks after rupturing his hamstring in the Rams' 18-16 loss to Arizona on October 18, 2026. The Rams' Week 7 line moved from -6 to -4.5 at Las Vegas.
How do injuries affect NFL betting lines?+
A starting quarterback is worth the most, often several points, as the Eagles showed when they went from a 3-point lookahead favorite to a 4.5 to 5.5-point underdog after Jalen Hurts was ruled out for the season. Skill players and linemen move lines less, and unresolved statuses usually move again when inactives are posted.
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